PKD1 Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-15660
宿主: Rabbit
反应性: H,M
应用: IHC
Overview
Synonyms | Autosomal dominant polycystic kidney disease 1 protein,Autosomal dominant polycystic kidney disease protein 1,nPKC-D1,nPKC-mu,OTTHUMP00000208669,OTTHUMP00000208670,PBP,Pc-1,PKD,Pkd1,PKD1,Polycystic Kidney Disease 1,polycystic kidney disease-associated protein,Polycystin 1 Precursor,Polycystin-1,Protein kinase C mu type,Protein kinase D,Serine/threonine-protein kinase D1,transient receptor potential cation channel,subfamily P,member 1,TRPP1,PKD1抗体 |
Swissprot | P98161 |
Source | Rabbit |
Reactivity | Human,Mouse |
Immunogen | Synthetic peptide of human PKD1 |
Application | IHC(Detection kit: E-IR-R213) |
Recommended dilution | IHC,,1:50-1:200 |
Concentration | 0.6 mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Membrane. |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
Background | This gene encodes a member of the polycystin protein family.The encoded glycoprotein contains a large N-terminal extracellular region, multiple transmembrane domains and a cytoplasmic C-tail.It is an integral membrane protein that functions as a regulator of calcium permeable cation channels and intracellular calcium homoeostasis.It is also involved in cell-cell/matrix interactions and may modulate G-protein-coupled signal-transduction pathways.It plays a role in renal tubular development, and mutations in this gene cause autosomal dominant polycystic kidney disease type 1 (ADPKD1). |
Images
Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PKD1 Polyclonal Antibody at dilution 1:50
Immunohistochemistry of paraffin-embedded Human breast cancer tissue using PKD1 Polyclonal Antibody at dilution 1:50
Immunohistochemistry of paraffin-embedded Kidney tissue using PKD1 Polyclonal Antibody at dilution of 1:60(Elabscience® Product Detected by Lifespan).