PLAT Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-12879
宿主: Rabbit
反应性: H
应用: WB,IHC
Overview
| Synonyms | Alteplase,DKFZp686I03148,Plasminogen activator tissue,Plasminogen activator tissue type,PLAT,Reteplase,t PA,T Plasminogen Activator,t-PA,T-plasminogen activator,Tissue plasminogen activator (t PA),Tissue type plasminogen activator,Tissue-type plasminogen activator chain B,tPA,TPA,TPA1,PLAT抗体 |
| Swissprot | P00750 |
| Source | Rabbit |
| Reactivity | Human |
| Immunogen | Synthetic peptide of human PLAT |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:200-1:1000;IHC,,1:50-1:200; |
| Concentration | 0.4 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Secreted>extracellular space. |
| Tissue specificity | Synthesized in numerous tissues (including tumors) and secreted into most extracellular body fluids, such as plasma, uterine fluid, saliva, gingival crevicular fluid, tears, seminal fluid, and milk. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | This gene encodes tissue-type plasminogen activator, a secreted serine protease which converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. Tissue-type plasminogen activator is synthesized as a single chain which is cleaved by plasmin to a two chain disulfide linked protein. This enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding; decreased activity leads to hypofibrinolysis which can result in thrombosis or embolism. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. |
Images
Western Blot analysis of 231 cell using PLAT Polyclonal Antibody at dilution of 1:450
Immunohistochemistry of paraffin-embedded Human lung cancer using PLAT Polyclonal Antibody at dilution of 1:50
Immunohistochemistry of paraffin-embedded Human esophagus cancer using PLAT Polyclonal Antibody at dilution of 1:50
