PLAUR Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-10547
宿主: Rabbit
反应性: H
应用: WB,IHC
Overview
| Synonyms | CD 87,CD87,CD87 antigen,MO 3,MO3,Monocyte activation antigen Mo3,Plasminogen activator receptor urokinase,Plasminogen activator urokinase receptor,PLAUR,U PAR,u plasminogen activator receptor,U-PAR,u-plasminogen activator receptor form 2,UPA receptor,uPAR,UPAR,Urinary plasminogen activator receptor,URKR,Urokinase plasminogen activator receptor,Urokinase plasminogen activator surface receptor,urokinase-type plasminogen activator (uPA) receptor,PLAUR抗体 |
| Swissprot | Q03405 |
| Source | Rabbit |
| Reactivity | Human |
| Immunogen | Recombinant protein of human PLAUR |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:500-1:2000;IHC,,1:50-1:200; |
| Concentration | 0.4 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Secreted and Cell membrane. |
| Tissue specificity | Expressed in neurons of the rolandic area of the brain (at protein level). Expressed in the brain. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol (GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined. |
Images
Western Blot analysis of A549 cell using PLAUR Polyclonal Antibody at dilution of 1:450
Immunohistochemistry of paraffin-embedded Human lung cancer using PLAUR Polyclonal Antibody at dilution of 1:60
Immunohistochemistry of paraffin-embedded Human cervical cancer using PLAUR Polyclonal Antibody at dilution of 1:60
