PLEKHA1 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-52629
宿主: Rabbit
反应性: H
应用: IHC
Overview
| Synonyms | OTTHUMP00000020651,PH domain containing family A member 1,PH domain-containing family A member 1,PKHA1,Pleckstrin homology domain containing A1,Pleckstrin homology domain containing family A member 1,Pleckstrin homology domain containing, family A (phosphoinositide binding specific) member,Pleckstrin homology domain-containing family A member 1,PLEKHA1,Tandem PH domain containing protein 1,Tandem PH domain-containing protein 1,TAPP 1,TAPP-1,TAPP1,PLEKHA1抗体 |
| Swissprot | Q9HB21 |
| Source | Rabbit |
| Reactivity | Human |
| Immunogen | Fusion protein of human PLEKHA1 |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:30-1:150 |
| Concentration | 1.08mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytoplasm. Cell membrane. Nucleus. Locates to the plasma membrane after treatments that stimulate the production of PtdIns3,4P2. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | This gene encodes a pleckstrin homology domain-containing adapter protein. The encoded protein is localized to the plasma membrane where it specifically binds phosphatidylinositol 3,4-bisphosphate. This protein may be involved in the formation of signaling complexes in the plasma membrane. Polymorphisms in this gene are associated with age-related macular degeneration. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 5. |
