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PLIN3 Polyclonal Antibody

规格: / 20μL / 60μL / 120μL / 200μL
价格: / ¥420 / ¥1010 / ¥1640 / ¥2365

货号:E-AB-16702

宿主: Rabbit

反应性: H

应用: IHC

  • 详情
  • Overview

    Synonyms 47 kDa mannose 6-phosphate receptor-binding protein,47 kDa MPR binding protein,47 kDa MPR-binding protein,Cargo selection protein TIP47,M6PRBP 1,M6PRBP1,Mannose 6 phosphate receptor binding protein 1,Mannose-6-phosphate receptor-binding protein 1,MGC11117,MGC2012,MPR binding protein 47 kDa,Perilipin 3,Perilipin-3,Perilipin3,Placental protein 17,PLIN3,PLIN3,pp17,Tail interacting protein 47 kD,TIP47,PLIN3抗体
    Swissprot O60664
    Source Rabbit
    Reactivity Human
    Immunogen Synthetic peptide of human PLIN3
    Application IHC(Detection kit: E-IR-R213)
    Recommended dilution IHC,,1:50-1:200
    Concentration 0.7mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Cytoplasm. Endosome membrane. Lipid droplet. Membrane associated on endosomes. Detected in the envelope and the core of lipid bodies and in lipid sails.
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
    Background Mannose 6-phophate receptors (MPRs) deliver lysosomal hydrolase from the Golgi to endosomes and then return to the Golgi complex. The protein encoded by this gene interacts with the cytoplasmic domains of both cation-independent and cation-dependent MPRs, and is required for endosome-to-Golgi transport. This protein also binds directly to the GTPase RAB9 (RAB9A), a member of the RAS oncogene family. The interaction with RAB9 has been shown to increase the affinity of this protein for its cargo. Multiple transcript variants encoding different isoforms have been found for this gene.
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