PMVK Polyclonal Antibody
| 规格： | / 60μL / 120μL / 200μL |
| 价格： | / ￥1380 / ￥2220 / ￥3300 |
货号：E-AB-70220
宿主: Rabbit
反应性: H
应用: IHC
Overview
| Synonyms | hPMK,HUMPMKI,OTTHUMP00000035546,Phosphomevalonate kinase,PMK,PMK PEN,PMKA,PMKase,PMKI,PMKPEN,PMVK,PMVK抗体 |
| Swissprot | Q15126 |
| Source | Rabbit |
| Reactivity | Human |
| Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse PMVK |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:1000-1:2000 |
| Concentration | 1.1 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytoplasm |
| Tissue specificity | Heart, liver, skeletal muscle, kidney, and pancreas. Lower level in brain, placenta and lung. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol. |
| Background | This gene encodes a peroxisomal enzyme that is a member of the galactokinase, homoserine kinase, mevalonate kinase, and phosphomevalonate kinase (GHMP) family of ATP-dependent enzymes. The encoded protein catalyzes the conversion of mevalonate 5-phosphate to mevalonate 5-diphosphate, which is the fifth step in the mevalonate pathway of isoprenoid biosynthesis. Mutations in this gene are linked to certain types of porokeratosis including disseminated superficial porokeratosis. Alternative splicing results in multiple transcript variants. |
