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PMVK Polyclonal Antibody

规格: / 60μL / 120μL / 200μL
价格: / ¥1380 / ¥2220 / ¥3300

货号:E-AB-70220

宿主: Rabbit

反应性: H

应用: IHC

  • 详情
  • Overview

    Synonyms hPMK,HUMPMKI,OTTHUMP00000035546,Phosphomevalonate kinase,PMK,PMK PEN,PMKA,PMKase,PMKI,PMKPEN,PMVK,PMVK抗体
    Swissprot Q15126
    Source Rabbit
    Reactivity Human
    Immunogen KLH conjugated Synthetic peptide corresponding to Mouse PMVK
    Application IHC(Detection kit: E-IR-R213)
    Recommended dilution IHC,,1:1000-1:2000
    Concentration 1.1 mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Cytoplasm
    Tissue specificity Heart, liver, skeletal muscle, kidney, and pancreas. Lower level in brain, placenta and lung.
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol.
    Background This gene encodes a peroxisomal enzyme that is a member of the galactokinase, homoserine kinase, mevalonate kinase, and phosphomevalonate kinase (GHMP) family of ATP-dependent enzymes. The encoded protein catalyzes the conversion of mevalonate 5-phosphate to mevalonate 5-diphosphate, which is the fifth step in the mevalonate pathway of isoprenoid biosynthesis. Mutations in this gene are linked to certain types of porokeratosis including disseminated superficial porokeratosis. Alternative splicing results in multiple transcript variants.
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