POMC Polyclonal Antibody
| 规格： | / 50μL / 100μL |
| 价格： | / ￥1010 / ￥1640 |
货号：E-AB-40635
宿主: Rabbit
反应性: M,R
应用: WB
Overview
| Synonyms | Pro-opiomelanocortin,Corticotropin-lipotropin,NPP,Melanotropin gamma,Gamma-MSH,Potential peptide,Corticotropin,ACTH,CLIP,Alpha-MSH,Beta-LPH,Gamma-LPH,Beta-MSH,Beta-endorphin,Met-enkephalin |
| Swissprot | P01189 |
| Source | Rabbit |
| Reactivity | Mouse,Rat |
| Immunogen | Synthetic peptide. |
| Application | WB(Detection kit: E-IR-R304) |
| Recommended dilution | WB,,1:1000-1:2000; |
| Concentration | 1.8mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Secreted |
| Isotype | IgG |
| Purification | Antigen Affinity Purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide,1% protective protein and 50% glycerol,pH7.4 |
| Background | Pro-opiomelanocortin (POMC) is a precursor protein expressed in the pituitary and the brain where it is processed into several peptide hormones and neuropeptides. Among these peptides are ACTH,α- and β-MSH,β-and γ-LPH,CLIP,β-endorphin,and N-POMC. POMC is involved in hypothalamic circuits regulating feeding behavior and POMC-producing neurons promote satiety. POMC neurons are also the target of leptin and insulin for the promotion of the browning of white fat. |
