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PPARG Polyclonal Antibody

规格: / 60μL / 120μL / 200μL
价格: / ¥1380 / ¥2220 / ¥3300

货号:E-AB-70309

宿主: Rabbit

反应性: H,M,R

应用: WB

  • 详情
  • 文献(5)
  • Overview

    Synonyms CIMT1,GLM1,NR1C3,Nuclear receptor subfamily 1 group C member 3,OTTHUMP00000185032,OTTHUMP00000185036,Peroxisome proliferator activated nuclear receptor gamma variant 1,Peroxisome proliferator activated receptor gamma 1,Peroxisome Proliferator Activated Receptor gamma,Peroxisome proliferator-activated receptor gamma,PPAR gamma,PPAR-gamma,PPARG,PPARG,PPARG1,PPARG2,PPARgamma,PPARG抗体
    Swissprot P37231,P37238,O88275
    Source Rabbit
    Reactivity Human,Mouse,Rat
    Immunogen Recombinant protein corresponding to Mouse PPARγ
    Application WB(Detection kit: E-IR-R304)
    Recommended dilution WB,,1:500-1:2000;
    Concentration 0.58 mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Nucleus.
    Tissue specificity Highest expression in adipose tissue. Lower in skeletal muscle, spleen, heart and liver. Also detectable in placenta, lung and ovary.Highest expression level in subcutaneous adipose tissue.
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol.
    Background This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described.
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