PPARG Polyclonal Antibody
规格: | / 60μL / 120μL / 200μL |
价格: | / ¥1380 / ¥2220 / ¥3300 |
货号:E-AB-70309
宿主: Rabbit
反应性: H,M,R
应用: WB
Overview
Synonyms | CIMT1,GLM1,NR1C3,Nuclear receptor subfamily 1 group C member 3,OTTHUMP00000185032,OTTHUMP00000185036,Peroxisome proliferator activated nuclear receptor gamma variant 1,Peroxisome proliferator activated receptor gamma 1,Peroxisome Proliferator Activated Receptor gamma,Peroxisome proliferator-activated receptor gamma,PPAR gamma,PPAR-gamma,PPARG,PPARG,PPARG1,PPARG2,PPARgamma,PPARG抗体 |
Swissprot | P37231,P37238,O88275 |
Source | Rabbit |
Reactivity | Human,Mouse,Rat |
Immunogen | Recombinant protein corresponding to Mouse PPARγ |
Application | WB(Detection kit: E-IR-R304) |
Recommended dilution | WB,,1:500-1:2000; |
Concentration | 0.58 mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Nucleus. |
Tissue specificity | Highest expression in adipose tissue. Lower in skeletal muscle, spleen, heart and liver. Also detectable in placenta, lung and ovary.Highest expression level in subcutaneous adipose tissue. |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol. |
Background | This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described. |
客户发表文献
- 文献: miR-3666 inhibits development of hepatic steatosis by negatively regulating PPARγ
样品类型: Cell sample - 文献: Lung mesenchymal stem cells-derived extracellular vesicles attenuate the inflammatory profile of Cystic Fibrosis epithelial cells
样品类型: Cell lysate - 文献: HIF-1α-l-PGDS-PPARγ regulates hypoxia-induced ANP secretion in beating rat atria
样品类型: Tissue homogenate - 文献: Vitexin alleviates non-alcoholic fatty liver disease by activating AMPK in high fat diet fed mice
样品类型: Tissue homogenate - 文献: Inhibition of Sphingolipid Synthesis as a Phenotype-Modifying Therapy in Cystic Fibrosis.
样品类型: Cell lysate