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PPOX Polyclonal Antibody

规格: / 20μL / 60μL / 120μL / 200μL
价格: / ¥420 / ¥1010 / ¥1640 / ¥2365

货号:E-AB-52754

宿主: Rabbit

反应性: H,M,R

应用: IHC

  • 详情
  • Overview

    Synonyms MGC8485,PPO,PPOX,PPOX,Protoporphyrinogen oxidase,V290M,Variegate porphyria,VP,PPOX抗体
    Swissprot P50336
    Source Rabbit
    Reactivity Human,Mouse,Rat
    Immunogen Fusion protein of human PPOX
    Application IHC(Detection kit: E-IR-R213)
    Recommended dilution IHC,,1:50-1:300
    Concentration 0.78mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Mitochondrion inner membrane.
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
    Background This gene encodes the penultimate enzyme of heme biosynthesis, which catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX.Mutations in this gene cause variegate porphyria, an autosomal dominant disorder of heme metabolism resulting from a deficiency in protoporphyrinogen oxidase, an enzyme located on the inner mitochondrial membrane.Alternatively spliced transcript variants encoding the same protein have been identified.
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