PPP1R15A Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-19394
宿主: Rabbit
反应性: H
应用: IHC
Overview
| Synonyms | Apoptosis associated protein,GADD 34,Growth arrest and DNA damage inducible 34,Growth arrest and DNA damage-inducible protein GADD34,Myeloid differentiation primary response protein MyD116 homolog,Ppp1r15a,PR15A,Protein phosphatase 1 regulatory (inhibitor) subunit 15A,Protein phosphatase 1 regulatory subunit 15A,PPP1R15A抗体 |
| Swissprot | O75807 |
| Source | Rabbit |
| Reactivity | Human |
| Immunogen | Synthetic peptide of human PPP1R15A |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:30-1:150 |
| Concentration | 1.8mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Endoplasmic reticulum. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | PPP1R15A (Protein Phosphatase 1 Regulatory Subunit 15A) is a Protein Coding gene. Diseases associated with PPP1R15A include Malignant Pleural Mesothelioma. Among its related pathways are Transcriptional activity of SMAD2/SMAD3-SMAD4 heterotrimer and Activation of cAMP-Dependent PKA. GO annotations related to this gene include protein kinase binding.This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The induction of this gene by ionizing radiation occurs in certain cell lines regardless of p53 status, and its protein response is correlated with apoptosis following ionizing radiation. |
