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PPY Polyclonal Antibody

规格: / 20μL / 60μL / 120μL / 200μL
价格: / ¥420 / ¥1010 / ¥1640 / ¥2365

货号:E-AB-18145

宿主: Rabbit

反应性: H,R

应用: WB

  • 详情
  • Overview

    Synonyms Pancreatic polypeptide,Pancreatic polypeptide Y,Pancreatic prohormone,PNP,PP,PPY,prepro-PP (prepropancreatic polypeptide),PPY抗体
    Swissprot P01298
    Source Rabbit
    Reactivity Human,Rat
    Immunogen Synthetic peptide of human PPY
    Application WB(Detection kit: E-IR-R304)
    Recommended dilution WB,,1:1000-1:5000;
    Concentration 3mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Secreted
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
    Background This gene encodes a member of the neuropeptide Y (NPY) family of peptides. The encoded 95 aa preproprotein is synthesized in the pancreatic islets of Langerhans and proteolytically processed to generate two peptide products. These products include the active pancreatic hormone of 36 aa and an icosapeptide of unknown function. This hormone acts as a regulator of pancreatic and gastrointestinal functions and may be important in the regulation of food intake. Plasma level of this hormone has been shown to be reduced in conditions associated with increased food intake and elevated in anorexia nervosa. In addition, infusion of this hormone in obese rodents has shown to decrease weight gain. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.
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