PRAME Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-52200
宿主: Rabbit
反应性: H
应用: IHC
Overview
| Synonyms | 4930534P07Rik,Cancer/testis antigen 130,CT130,MAPE,Melanoma antigen preferentially expressed in tumors,OIP 4,OIP-4,OIP4 ,OPA interacting protein 4,Opa interacting protein OIP4,OPA-interacting protein 4,PRAME,PRAME,Preferentially expressed antigen in melanoma ,Preferentially expressed antigen of melanoma,RP23-250F8.3,PRAME抗体 |
| Swissprot | P78395 |
| Source | Rabbit |
| Reactivity | Human |
| Immunogen | Fusion protein of human PRAME |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:40-1:250 |
| Concentration | 1.1mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Nucleus. Cell membrane. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | This gene encodes an antigen that is preferentially expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues, except testis. The encoded protein acts as a repressor of retinoic acid receptor, and likely confers a growth advantage to cancer cells via this function. Alternative splicing results in multiple transcript variants. |
