PRMT7 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-10554
宿主: Rabbit
反应性: H
应用: WB
Overview
| Synonyms | [Myelin basic protein]-arginine N-methyltransferase PRMT7,ANM7,FLJ10640,Histone-arginine N-methyltransferase PRMT7,KIAA1933,Myelin basic protein arginine N methyltransferase,OTTHUMP00000174863,PRMT7,Protein arginine methyltransferase 7,Protein arginine N-methyltransferase 7,PRMT7抗体 |
| Swissprot | Q9NVM4 |
| Source | Rabbit |
| Reactivity | Human |
| Immunogen | Recombinant protein of human PRMT7 |
| Application | WB(Detection kit: E-IR-R304) |
| Recommended dilution | WB,,1:500-1:2000; |
| Concentration | 0.2 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytoplasm, cytosol. Nucleus. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | Protein arginine methyltransferase 7 is a protein that in humans is encoded by the PRMT7 gene.Arginine methylation is an apparently irreversible protein modification catalyzed by arginine methyltransferases, such as PMT7, using S-adenosylmethionine (AdoMet) as the methyl donor.Arginine methylation is implicated in signal transduction, RNA transport, and RNA splicing.May be involved in etoposide-induced cytotoxicity, a chemotherapeutic agent frequently used for testicular cancer and small-cell lung cancer that can cause cytotoxicity in the treatment of other cancers.Down-regulation confers increased sensitivity to the Top1 inhibitor camptothecin (CPT). |
