PSMA3 Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-18804
宿主: Rabbit
反应性: H,M,R
应用: WB,IHC
Overview
Synonyms | HC8,Macropain subunit C8,MGC12306,MGC32631,Multicatalytic endopeptidase complex subunit C8,Proteasome (prosome macropain) subunit alpha type 3,Proteasome alpha 3 subunit,Proteasome component C8,Proteasome subunit alpha type 3,Proteasome subunit alpha type-3,Proteasome subunit C8,PSA3,PSC8,psmA3,PSMA3抗体 |
Swissprot | P25788 |
Source | Rabbit |
Reactivity | Human,Mouse,Rat |
Immunogen | Fusion protein of human PSMA3 |
Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
Recommended dilution | WB,,1:500-1:2000;IHC,,1:50-1:300; |
Concentration | 0.9mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Cytoplasm. Nucleus. |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
Background | The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Two alternative transcripts encoding different isoforms have been identified. |
Images
Western blot analysis of Hela cell Mouse spleen tissue Mouse liver tissue PC3 cell HL60 cell A549 cell NIH/3T3 cell lysates using PSMA3 Polyclonal Antibody at dilution of 1:350
Immunohistochemistry of paraffin-embedded Human lung cancer tissue using PSMA3 Polyclonal Antibody at dilution of 1:50(×200)
Immunohistochemistry of paraffin-embedded Human prost ate cancer tissue using PSMA3 Polyclonal Antibody at dilution of 1:50(×200)