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PTGDR2 Polyclonal Antibody

规格: / 20μL / 60μL / 120μL / 200μL
价格: / ¥420 / ¥1010 / ¥1640 / ¥2365

货号:E-AB-18034

宿主: Rabbit

反应性: H,M,R

应用: IHC

  • 详情
  • Overview

    Synonyms CD294,CD294 antigen,Chemoattractant receptor homologous molecule expressed on Th2 cells,chemoattractant receptor-homologous,Chemoattractant receptor-homologous molecule expressed on Th2 cells,CRTH 2,CRTH2,DL1R,DP2 prostaglandin receptor,G Protein Coupled Receptor 44,GPR 44,Gpr44,GPR44,PTGDR2,Putative G protein coupled receptor 44,Putative G-protein coupled receptor 44,PTGDR2抗体
    Swissprot Q9Y5Y4
    Source Rabbit
    Reactivity Human,Mouse,Rat
    Immunogen Synthetic peptide of human PTGDR2
    Application IHC(Detection kit: E-IR-R213)
    Recommended dilution IHC,,1:30-1:150
    Concentration 0.78mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Cell membrane.
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
    Background This gene encodes a G-protein-coupled receptor that is preferentially expressed in CD4+ effector T helper 2 (Th2) cells. This protein is a prostaglandin D2 receptor that mediates the pro-inflammatory chemotaxis of eosinophils, basophils, and Th2 lymphocytes generated during allergic inflammation. Single nucleotide polymorphisms in the 3' UTR of this gene have been associated with asthma susceptibility.PTGDR2 (Prostaglandin D2 Receptor 2) is a Protein Coding gene. Diseases associated with PTGDR2 include Folliculitis and Eosinophilic Pustular Folliculitis. Among its related pathways are Peptide ligand-binding receptors and Ibuprofen Pathway, Pharmacodynamics. GO annotations related to this gene include G-protein coupled receptor activity and prostaglandin F receptor activity. An important paralog of this gene is FPR3.
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