PTH1R Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-18982
宿主: Rabbit
反应性: H,M,R
应用: IHC
Overview
Synonyms | MGC138426,MGC138452,Parathyroid hormone 1 receptor,Parathyroid hormone/parathyroid hormone related peptide receptor,Parathyroid hormone/parathyroid hormone related protein receptor,Parathyroid hormone/parathyroid hormone-related peptide receptor,PTH receptor,PTH/PTHr receptor,PTH/PTHrP receptor,PTH/PTHrP type I receptor,PTH1 receptor,PTH1R,PTH1R,PTHR 1,PTHR,PTHR1,PTH1R抗体 |
Swissprot | Q03431 |
Source | Rabbit |
Reactivity | Human,Mouse,Rat |
Immunogen | Fusion protein of human PTH1R |
Application | IHC(Detection kit: E-IR-R213) |
Recommended dilution | IHC,,1:50-1:300 |
Concentration | 1.14mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Cell membrane. |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
Background | The protein encoded by this gene is a member of the G-protein coupled receptor family 2. This protein is a receptor for parathyroid hormone (PTH) and for parathyroid hormone-like hormone (PTHLH). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. Defects in this receptor are known to be the cause of Jansen's metaphyseal chondrodysplasia (JMC), chondrodysplasia Blomstrand type (BOCD), as well as enchodromatosis. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, May 2010] |