PTN Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-12851
宿主: Rabbit
反应性: H,M,R
应用: WB
Overview
| Synonyms | HARP,HB-GAM,HBBM,HBGAM,HBGF-8,HBGF8,HBNF,HBNF-1,HBNF1,heparin affin regulatory protein,Heparin binding growth associated molecule,Heparin binding growth factor 8,Heparin binding neurite outgrowth promoting factor 1,Heparin-binding brain mitogen,Heparin-binding growth factor 8,Heparin-binding growth-associated molecule,heparin-binding neurite outgrowth promoting factor,Heparin-binding neurite outgrowth-promoting factor 1,NEGF1,Neurite growth promoting factor 1,Neurite outgrowth-promoting factor,heparin-binding,OSF-1,OSF1,Osteoblast-specific factor 1,pleiotrophin (heparin binding growth factor 8,neurite growth-promoting factor 1),Pleiotrophin,PTN,PTN,PTN抗体 |
| Swissprot | P21246 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Synthetic peptide of human PTN |
| Application | WB(Detection kit: E-IR-R304) |
| Recommended dilution | WB,,1:500-1:2000; |
| Concentration | 0.3 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Secreted. |
| Tissue specificity | Osteoblast and brain. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | Pleiotrophin (PTN) also known as heparin-binding brain mitogen (HBBM) or heparin-binding growth factor 8 (HBGF-8) or neurite growth-promoting factor 1 (NEGF1) or heparin affinity regulatory peptide (HARP) or heparin binding growth associated molecule (HB-GAM) is a protein that in humans is encoded by the PTNgene.Pleiotrophin is an 18-kDa growth factor that has a high affinity for heparin.It is structurally related to midkine and retinoic acid induced heparin-binding protein.Secreted growth factor that induces neurite outgrowth and which is mitogenic for fibroblasts, epithelial, and endothelial cells.Binds anaplastic lymphoma kinase (ALK) which induces MAPK pathway activation, an important step in the anti-apoptotic signaling of PTN and regulation of cell proliferation. |
