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PTPRA Polyclonal Antibody

规格: / 20μL / 60μL / 120μL / 200μL
价格: / ¥420 / ¥1010 / ¥1640 / ¥2365

货号:E-AB-52203

宿主: Rabbit

反应性: H,M,R

应用: WB

  • 详情
  • Overview

    Synonyms HEPTP,HLPR,HPTP alpha,HPTPA,HPTPalpha,Leukocyte common antigen related peptide,LRP,Protein tyrosine phosphatase alpha,Protein tyrosine phosphatase receptor type A,Protein tyrosine phosphatase receptor type alpha polypeptide,Protein tyrosine phosphate,Protein-tyrosine phosphatase alpha,PTPA,PTPalpha,PTPase alpha,PTPLCA related phosphatase,Ptpra,PTPRA,PTPRL 2,PTPRL2,PTRA,R PTP alpha,R-PTP-alpha,Receptor type tyrosine protein phosphatase alpha,Receptor-type tyrosine-protein phosphatase alpha,RPTPA,Tyrosine phosphatase alpha,PTPRA抗体
    Swissprot P18433
    Source Rabbit
    Reactivity Human,Mouse,Rat
    Immunogen Fusion protein of human PTPRA
    Application WB(Detection kit: E-IR-R304)
    Recommended dilution WB,,1:500-1:2000;
    Concentration 0.6mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Membrane.
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
    Background The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. This PTP has been shown to dephosphorylate and activate Src family tyrosine kinases, and is implicated in the regulation of integrin signaling, cell adhesion and proliferation. Three alternatively spliced variants of this gene, which encode two distinct isoforms, have been reported.
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