Purified Anti-Human CD11a Antibody[R7-1]
| 规格： | / 25μg / 100μg |
| 价格： | / ￥344 / ￥768 |
货号：E-AB-F1211A
货期：咨询
宿主: Mouse
反应性: H
应用: FCM
Overview
| Synonyms | CD11A;ITGAL;Integrin alpha-L;LFA-1A |
| Swissprot | P20701 |
| Source | Mouse |
| Reactivity | Human |
| Application | FCM |
| Recommended dilution | FCM,,2 μg/mL(1×10^5-5×10^5 cells) |
| Concentration | 0.5mg/mL |
| Clonality | Monoclonal |
Properties
| Clone No | R7-1 |
|---|---|
| Isotype | Mouse IgG1, κ |
| Conjugation | Unconjugated |
| Storage instructions | This product can be stored at 2-8°C for 12 months. Do not freeze. |
| Storage buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer. |
| Background | CD11a is a 170-180 kD type I transmembrane glycoprotein also known as LFA-1α chain and integrin αL subunit. CD11a non-covalently associates with integrin β2 (CD18) to form LFA-1. It is expressed on all leukocytes, including B and T lymphocytes, monocytes, macrophages, neutrophils, basophils and eosinophils. It is absent on non-hematopoietic tissues and platelets. CD11a plays a central role in leukocyte cell-cell interactions and is important in lymphocyte costimulation. CD11a/CD18 binds to ICAM-1 (CD54), ICAM-2 (CD102), and ICAM-3 (CD50). |
