Purified Anti-Human CD197 Antibody[G043H7]
| 规格： | |
| 价格： |
货号：E-AB-F11590P
货期：7~10 days
宿主: Mouse
反应性: H
应用: FCM
Overview
| Synonyms | EBI;CDw;BLR;EVI;CMKBR;CC-CKR;CCR;CCR7;BLR2;CC-CKR-7;CCR-7;CD197;CDw197;CMKBR7;EBI1;EVI1; EBI-1; BLR-2; CMKBR7 |
| Swissprot | P32248 |
| Source | Mouse |
| Reactivity | Human |
| Immunogen | Recombinant Human CD197 protein |
| Application | FCM |
| Recommended dilution | FCM,,2 μg/mL(1×10^5-5×10^5 cells) |
| Concentration | ≥ 1 mg/mL |
Properties
| Clone No | G043H7 |
|---|---|
| Isotype | Mouse IgG2a, κ |
| Purification | > 98%, Protein A/G purified |
| Conjugation | Unconjugated |
| Storage instructions | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
| Storage buffer | Phosphate buffered solution, pH 7.2, containing 0.05% proclin 300. |
| Background | The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. Signals mediated by this receptor regulate T cell homeostasis in lymph nodes, and may also function in the activation and polarization of T cells, and in chronic inflammation pathogenesis. Alternative splicing of this gene results in multiple transcript variants. |
