Purified Anti-Human CD20 Antibody[2H7]
| 规格： | / 25μg / 100μg |
| 价格： | / ￥336 / ￥624 |
货号：E-AB-F1212A
货期：咨询
宿主: Mouse
反应性: H
应用: FCM
Overview
| Synonyms | B-lymphocyte surface antigen B1;Bp35;Leukocyte surface antigen Leu-16;MS4A1 |
| Swissprot | P11836 |
| Source | Mouse |
| Reactivity | Human |
| Immunogen | Recombinant Human CD20 protein |
| Application | FCM |
| Recommended dilution | FCM,,2 μg/mL(1×10^5-5×10^5 cells) |
| Concentration | 1mg/mL |
| Clonality | Monoclonal |
Properties
| Clone No | 2H7 |
|---|---|
| Isotype | Mouse IgG2b, κ |
| Purification | >98%, Protein A/G purified |
| Conjugation | Unconjugated |
| Storage instructions | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
| Storage buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer. |
| Background | CD20 is a 33-37 kD, four transmembrane spanning protein, also known as B1 and Bp35. CD20 is expressed on pre-B-cells, resting and activated B cells (not plasma cells), some follicular dendritic cells, and at low levels on a T cell subset. CD20 is heavily phosphorylated on activated B cells and malignant B cells. Homo-oligomeric complexes of CD20 are thought to form Ca2+ conductive ion channels in the plasma membrane of B cells. The CD20 molecule is involved in B-cell activation and is associated with various Src family kinases (Lyn, Lck, Fyn). It exists in a complex with MHC class I and II, CD53, CD81, and CD82. |
