Purified Anti-Human CD35 Antibody[E11]
规格: | / 25μg / 100μg |
价格: | / ¥288 / ¥720 |
货号:E-AB-F1062A
货期:咨询
宿主: Mouse
反应性: H
应用: FCM
Overview
Synonyms | C3BR;C3b/C4b receptor;CD35;CR1;Complement receptor type 1 |
Swissprot | P17927 |
Source | Mouse |
Reactivity | Human |
Application | FCM |
Concentration | 0.5mg/mL |
Clonality | Monoclonal |
Properties
Clone No | E11 |
---|---|
Isotype | Mouse IgG1, κ |
Conjugation | Unconjugated |
Storage instructions | This product can be stored at 2-8°C for 12 months. Do not freeze. |
Storage buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer. |
Background | CD35 is a type I single chain of glycoprotein, also known as C3b/C4b receptor, Complement Receptor type 1 or CR1. Four molecular weight allotypes (160kD, 190kD, 220kD, and 250kD) have been described. CD35 is expressed on granulocytes, monocytes, B cells, erythrocytes, and follicular dendritic cells, as well as subsets of NK and T cells. CD35 binds complement C3b, C4b, or iC3, and iC4, and plays important roles in both innate and adoptive immune response via mediating phagocytosis by granulocytes and monocytes. CD35 has also been reported to inhibit T-cell proliferation. |