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Purified Anti-Human CD35 Antibody[E11]

规格: / 25μg / 100μg
价格: / ¥288 / ¥720

货号:E-AB-F1062A

货期:咨询

宿主: Mouse

反应性: H

应用: FCM

  • 详情
  • Overview

    Synonyms C3BR;C3b/C4b receptor;CD35;CR1;Complement receptor type 1
    Swissprot P17927
    Source Mouse
    Reactivity Human
    Application FCM
    Concentration 0.5mg/mL
    Clonality Monoclonal

    Properties

    Clone No E11
    Isotype Mouse IgG1, κ
    Conjugation Unconjugated
    Storage instructions This product can be stored at 2-8°C for 12 months. Do not freeze.
    Storage buffer Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer.
    Background CD35 is a type I single chain of glycoprotein, also known as C3b/C4b receptor, Complement Receptor type 1 or CR1. Four molecular weight allotypes (160kD, 190kD, 220kD, and 250kD) have been described. CD35 is expressed on granulocytes, monocytes, B cells, erythrocytes, and follicular dendritic cells, as well as subsets of NK and T cells. CD35 binds complement C3b, C4b, or iC3, and iC4, and plays important roles in both innate and adoptive immune response via mediating phagocytosis by granulocytes and monocytes. CD35 has also been reported to inhibit T-cell proliferation.
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