Purified Anti-Human CD58 Antibody[TS2/9.1]
规格: | / 25μg / 100μg |
价格: | / ¥288 / ¥864 |
货号:E-AB-F1068A
货期:咨询
宿主: Mouse
反应性: H
应用: FCM
Overview
Synonyms | Ag3;CD58;LFA3;Lymphocyte function-associated antigen 3;Surface glycoprotein LFA-3 |
Swissprot | P19256 |
Source | Mouse |
Reactivity | Human |
Application | FCM |
Recommended dilution | FCM,,2 μg/mL(1×10^5-5×10^5 cells) |
Concentration | 0.5mg/mL |
Clonality | Monoclonal |
Properties
Clone No | TS2/9.1 |
---|---|
Isotype | Mouse IgG1, κ |
Conjugation | Unconjugated |
Storage instructions | This product can be stored at 2-8°C for 12 months. Do not freeze. |
Storage buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer. |
Background | CD58, also known as lymphocyte function-associated antigen 3 (LFA-3) is a 45-70 kD cell surface protein that is a member of the immunoglobulin superfamily. Alternative splicing of CD58 gives rise to transmembrane and glycosylphosphatidylinositol (GPI)-anchored forms on cell surface. CD58 is expressed on both hematopoietic and non-hematopoietic cells including B cells, T cells, monocytes, erythrocytes, endothelial cells, epithelial cells, and fibroblasts. High levels are observed on memory T cells and dendritic cells. CD58 expressed on antigen presenting cells and target cells enhances T cell recognition via the binding of it's cognate ligand, CD2, on the T cell surface. |