Purified Anti-Human CD62L Antibody[DREG56]
| 规格： | / 25μg / 100μg |
| 价格： | / ￥240 / ￥720 |
货号：E-AB-F1051A
货期：咨询
宿主: Mouse
反应性: H
应用: FCM
Overview
| Synonyms | CD62L;CD62 antigen-like family member L;L-selectin;LAM-1;LECAM1;Lnhr;Ly-22;Ly22;Lymph node homing receptor;Sell |
| Swissprot | P14151 |
| Source | Mouse |
| Reactivity | Human |
| Application | FCM |
| Recommended dilution | FCM,,2 μg/mL(1×10^5-5×10^5 cells) |
| Concentration | 0.5mg/mL |
| Clonality | Monoclonal |
Properties
| Clone No | DREG56 |
|---|---|
| Isotype | Mouse IgG1, κ |
| Conjugation | Unconjugated |
| Storage instructions | This product can be stored at 2-8°C for 12 months. Do not freeze. |
| Storage buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer. |
| Background | CD62L is a 74-95 kD single chain type I glycoprotein referred to as L-selectin or LECAM-1. It is expressed on most peripheral blood B cells, subsets of T and NK cells, monocytes, granulocytes, and certain hematopoietic malignant cells. CD62L binds to carbohydrates present on certain glycoforms of CD34, glycam-1, and MAdCAM-1 and with a low affinity to anionic oligosaccharide sequences related to sialylated Lewis X (sLex, CD15s) through its C-type lectin domain. CD62L is important for the homing of naïve lymphocytes to high endothelial venules in peripheral lymph nodes and Peyer's patches. It also plays a role in leukocyte rolling on activated endothelial cells. |
