Purified Anti-Human CD86 Antibody[BU63]
| 规格： | / 25μg / 100μg |
| 价格： | / ￥440 / ￥1280 |
货号：E-AB-F1012A
货期：咨询
宿主: Mouse
反应性: H
应用: FCM;Block
Overview
| Synonyms | Activation B7-2 antigen;Cd86;ETC-1;Early T-cell costimulatory molecule 1;T-lymphocyte activation antigen CD86 |
| Swissprot | P42081 |
| Source | Mouse |
| Reactivity | Human |
| Application | FCM;Block |
| Recommended dilution | FCM,,2 μg/mL(1×10^5-5×10^5 cells) |
| Concentration | 0.5mg/mL |
| Clonality | Monoclonal |
Properties
| Clone No | BU63 |
|---|---|
| Isotype | Mouse IgG1, κ |
| Conjugation | Unconjugated |
| Storage instructions | This product can be stored at 2-8°C for 12 months. Do not freeze. |
| Storage buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer. |
| Background | CD86 is an 80 kD immunoglobulin superfamily member also known as B7-2, B70, and Ly-58. CD86 is expressed on activated B and T cells, monocytes/macrophages, dendritic cells, and astrocytes. CD86, along with CD80, is the ligand of CD28 and CD152 (CTLA-4). CD86 is expressed earlier in the immune response than CD80. CD86 has also been shown to be involved in immunoglobulin class-switching and triggering of NK cell-mediated cytotoxicity. CD86 binds to CD28 to transduce costimulatory signals for T cell activation, proliferation, and cytokine production. CD86 can bind to CD152 as well, also known as CTLA-4, to deliver an inhibitory signal to T cells. |
