Purified Anti-Human/Monkey CD154/CD40L Antibody[5C8]
规格: | / 25μg / 100μg |
价格: | / ¥432 / ¥1200 |
货号:E-AB-F1128A
货期:咨询
宿主: Mouse
反应性: H;MK
应用: FCM
Overview
Synonyms | T-BAM; TNFSF5; TRAP; gp39;CD40L |
Swissprot | P29965 |
Source | Mouse |
Reactivity | Human;Monkey |
Application | FCM |
Concentration | 0.5mg/mL |
Clonality | Monoclonal |
Properties
Clone No | 5C8 |
---|---|
Isotype | Mouse IgG2a, κ |
Conjugation | Unconjugated |
Storage instructions | This product can be stored at 2-8°C for 12 months. Do not freeze. |
Storage buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer. |
Background | CD154 (CD40 ligand) is also known as CD40L, gp39, TRAP and T-BAM. CD40 ligand is a 32-39 kD type II transmembrane glycoprotein. It is a member of the TNF superfamily and is expressed on activated T cells. It has been reported to be important for B cell costimulation following binding of its receptor, CD40. Additionally, binding of CD40L to CD40 on B cells promotes the secretion of immunoglobulin and Ig isotype switching. CD40L is also involved in the regulation of cytokine production by T cells. |