Purified Anti-Human/Mouse/Rat CD47 Antibody[MIAP410]
| 规格： | / 25μg / 100μg |
| 价格： | / ￥280 / ￥768 |
货号：E-AB-F1016A
货期：咨询
宿主: Mouse
反应性: H;M;R
应用: FCM
Overview
| Synonyms | Cd47;IAP;Integrin-associated protein;Leukocyte surface antigen CD47 |
| Swissprot | Q08722,Q61735,P97829 |
| Source | Mouse |
| Reactivity | Human;Mouse;Rat |
| Application | FCM |
| Recommended dilution | FCM,,2 μg/mL(1×10^5-5×10^5 cells) |
| Concentration | 0.5mg/mL |
| Clonality | Monoclonal |
Properties
| Clone No | MIAP410 |
|---|---|
| Isotype | Mouse IgG1, κ |
| Conjugation | Unconjugated |
| Storage instructions | This product can be stored at 2-8°C for 12 months. Do not freeze. |
| Storage buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer. |
| Background | CD47, also known as Integrin-Associated Protein (IAP), is a membrane protein of about 50 kD with an IgV-like extracelluluar domain, a five membrane-spanning segment and a short terminal cytoplasmic region. It is widely expressed on many cell types and often associated with beta 3 integrins. It has been reported that CD47 functions as a self marker. Red cells lacking CD47 were rapidly cleared from the bloodstream by splenic macrophages. By binding to SIRPα, CD47 controls hemostatic innate immune functions, such as phagocytosis and cell trafficking. |
