Purified Anti-Mouse CD183/CXCR3 Antibody[CXCR3-173]
规格: | / 25μg / 100μg |
价格: | / ¥336 / ¥640 |
货号:E-AB-F1114A
货期:咨询
宿主: Armenian Hamster
反应性: M
应用: FCM
Overview
Synonyms | C-X-C chemokine receptor type 3;CD183/CXCR3;CXC-R3;CXCR-3;Cxcr3;IP-10 receptor;Interferon-inducible protein 10 receptor |
Swissprot | O88410 |
Source | Armenian Hamster |
Reactivity | Mouse |
Application | FCM |
Recommended dilution | FCM,,2 μg/mL(1×10^5-5×10^5 cells) |
Concentration | 0.5mg/mL |
Clonality | Monoclonal |
Properties
Clone No | CXCR3-173 |
---|---|
Isotype | Armenian Hamster IgG |
Conjugation | Unconjugated |
Storage instructions | This product can be stored at 2-8°C for 12 months. Do not freeze. |
Storage buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer. |
Background | CD183/CXCR3, also known as CXCR3, is a member of the C-X-C chemokine family, characterized by a pair of cysteine residues separated by a single amino acid. CXCR3 is a 38 kD seven pass transmembrane receptor coupled to G-protein. It mediates Ca2+ mobilization and chemotaxis in response to C-X-C chemokines, such as IP10 (CXCL10), MIG (CXCL9), I-TAC (CXCL11) and PF4 (CXCL4). CXCR3 is expressed primarily on activiated T lymphocytes, NK cells, and some epithelial cells and endothelial cells. It is not expressed on B cells, monocytes or granulocytes. |