Purified Anti-Mouse CD210/IL-10R Antibody[1B1.3A]
规格: | / 25μg / 100μg |
价格: | / ¥240 / ¥640 |
货号:E-AB-F1036A
货期:咨询
宿主: Rat
反应性: M
应用: FCM
Overview
Synonyms | IL-10R subunit alpha;CD210;CDw210a;IL-10 receptor subunit alpha;IL-10R subunit 1;IL-10R1;IL-10RA;Il10ra;Interleukin-10 receptor subunit 1;Interleukin-10 receptor subunit alpha |
Swissprot | Q61727 |
Source | Rat |
Reactivity | Mouse |
Application | FCM |
Concentration | 0.5mg/mL |
Clonality | Monoclonal |
Properties
Clone No | 1B1.3A |
---|---|
Isotype | Rat IgG1, κ |
Conjugation | Unconjugated |
Storage instructions | This product can be stored at 2-8°C for 12 months. Do not freeze. |
Storage buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer. |
Background | CD210 is a 90-110 kD IL-10 receptor. It is a class II cytokine receptor expressed on thymocytes, T cells, B cells, NK cells, monocytes and macrophages. Ligand binding of CD210 induces Jak1 and Tyk, resulting in STAT1 and STAT3 activation. IL-10 receptor stimulation results in the inhibition of cytokine production and the costimulation of B cell proliferation and differentiation. The only known ligand for this receptor is IL-10. |