Purified Anti-Mouse CD366/Tim-3 Antibody[RMT3-23]
| 规格： | / 25μg / 100μg |
| 价格： | / ￥360 / ￥768 |
货号：E-AB-F1192A
货期：咨询
宿主: Rat
反应性: M
应用: FCM
Overview
| Synonyms | TIMD3;HAVcr-2;TIM3;TIMD-3 |
| Swissprot | Q8VIM0 |
| Source | Rat |
| Reactivity | Mouse |
| Application | FCM |
| Concentration | 0.5mg/mL |
| Clonality | Monoclonal |
Properties
| Clone No | RMT3-23 |
|---|---|
| Isotype | Rat IgG2a, κ |
| Conjugation | Unconjugated |
| Storage instructions | This product can be stored at 2-8°C for 12 months. Do not freeze. |
| Storage buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer. |
| Background | CD366 (Tim-3) is a transmembrane protein also known as T cell immunoglobulin and mucin domain containing protein-3. Tim-3 is expressed at high levels on activated T cells (preferentially on Th1 cells, monocytes/macrophages, and dendritic cells). Tim-3 has also been shown to exist as a soluble protein. Cells expressing Tim-3 are present at high levels in the CNS of animals at the onset of experimental autoimmune encephalomyelitis (EAE), a disease mediated by lymphocytes secreting Th1-like cytokines. Tim-3 has been proposed to inhibit Th1-mediated immune responses and promote immunological tolerance. |
