Purified Anti-Mouse CD3 Antibody[17A2]
| 规格: | / 25μg / 100μg |
| 价格: | / ¥120 / ¥416 |
货号:E-AB-F1013A
货期:咨询
宿主: Rat
反应性: M
应用: FCM
Overview
| Synonyms | CD3;CD3E/D/G/Z;CD3e/d/g/z;T-cell surface glycoprotein CD 3epsilon/delta/gamma/zeta chain |
| Swissprot | P04235,P11942,P22646,P24161 |
| Source | Rat |
| Reactivity | Mouse |
| Immunogen | Recombinant Mouse CD3 protein |
| Application | FCM |
| Recommended dilution | FCM,,2 μg/mL(1×10^5-5×10^5 cells) |
| Concentration | 1mg/mL |
| Clonality | Monoclonal |
Properties
| Clone No | 17A2 |
|---|---|
| Isotype | Rat IgG2b, κ |
| Purification | >98%, Protein A/G purified |
| Conjugation | Unconjugated |
| Storage instructions | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
| Storage buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer. |
| Background | CD3, also known as T3, is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3 is composed of CD3ε, δ, γ and ζ chains. It forms a TCR complex by associating with TCR α/β or γ/δ chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex. |
