Purified Anti-Mouse CD45.2 Antibody[104.2]
规格: | / 25μg / 100μg |
价格: | / ¥96 / ¥344 |
货号:E-AB-F1122A
货期:咨询
宿主: Mouse
反应性: M
应用: FCM
Overview
Synonyms | LCA;Ly-5.2 |
Source | Mouse |
Reactivity | Mouse |
Application | FCM |
Concentration | 0.5mg/mL |
Clonality | Monoclonal |
Properties
Clone No | 104.2 |
---|---|
Isotype | Mouse IgG2a, κ |
Conjugation | Unconjugated |
Storage instructions | This product can be stored at 2-8°C for 12 months. Do not freeze. |
Storage buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer. |
Background | CD45.2 is an alloantigen of CD45, expressed by Ly5.2 bearing mouse strains (e.g., A, AKR, BALB/c, CBA/Ca, CBA/J, C3H/He, C57BL, C57BR, C57L, C58, DBA/1, DBA/2, NZB, SWR, 129). CD45, a member of the protein tyrosine phosphatase (PTP) family, is a 180-240 kD glycoprotein expressed on all hematopoietic cells except mature erythrocytes and platelets. There are multiple isoforms in the mouse that play key roles in TCR and BCR signal transduction. These isoforms are very specific to the activation and maturation states of the cell as well as specific cell type. The primary ligands for CD45 are galectin-1, CD2, CD3, CD4, TCR, CD22, and Thy-1. |