Purified Anti-Mouse CD90.2/Thy1.2 Antibody[30H12]
| 规格： | / 25μg / 100μg |
| 价格： | / ￥240 / ￥640 |
货号：E-AB-F1094A
货期：咨询
宿主: Rat
反应性: M
应用: FCM
Overview
| Synonyms | CD90.2;Thy-1.2;Thy-1.2 antigen;Thy-1.2 membrane glycoprotein;Thy1.2 |
| Source | Rat |
| Reactivity | Mouse |
| Immunogen | Recombinant Mouse CD90.2 protein |
| Application | FCM |
| Recommended dilution | FCM,,2 μg/mL(1×10^5-5×10^5 cells) |
| Concentration | 1mg/mL |
| Clonality | Monoclonal |
Properties
| Clone No | 30H12 |
|---|---|
| Isotype | Rat IgG2b, κ |
| Purification | >98%, Protein A/G purified |
| Conjugation | Unconjugated |
| Storage instructions | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
| Storage buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer. |
| Background | CD90.2 is a 25-35 kD immunoglobulin superfamily member also known as Thy1.2. It is expressed on hematopoietic stem cells and neurons, all thymocytes, and peripheral T cells in Thy1.2 bearing mouse strains (Balb/c, CBA/J, C3H/He, C57BL/-, DBA, NZB/-). CD90.2 is a glycosylphosphatidylinositol (GPI)-anchored membrane glycoprotein involved in signal transduction. CD90.2 is involved in costimulation of lymphocyte proliferation and induction of hematopoietic stem cells differentiation. CD90.2 has been shown to interact with CD45. The 30H12 antibody has been reported to induce Ca2+ flux in thymocytes and, in combination with antibody against the CD3/TCR complex, promote thymocyte apoptosis and inhibit CD3-mediated proliferative responses of mature T lymphocytes. |
