Purified Anti-Mouse/Human CD11b Antibody[M1/70]
| 规格： | / 25μg / 100μg |
| 价格： | / ￥128 / ￥416 |
货号：E-AB-F1081A
货期：咨询
宿主: Rat
反应性: H;M
应用: FCM
Overview
| Synonyms | CD11 antigen-like family member B;CD11b;CR-3 alpha chain;Integrin alpha-M;Itgam;Leukocyte adhesion receptor MO1 |
| Swissprot | P05555,P11215 |
| Source | Rat |
| Reactivity | Human;Mouse |
| Application | FCM |
| Recommended dilution | FCM,,2 μg/mL(1×10^5-5×10^5 cells) |
| Concentration | 0.5mg/mL |
| Clonality | Monoclonal |
Properties
| Clone No | M1/70 |
|---|---|
| Isotype | Rat IgG2b, κ |
| Conjugation | Unconjugated |
| Storage instructions | This product can be stored at 2-8°C for 12 months. Do not freeze. |
| Storage buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer. |
| Background | CD11b is a 170 kD glycoprotein also known as αM integrin, Mac-1 α subunit, Mol, CR3, and Ly-40. CD11b is a member of the integrin family, primarily expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b non-covalently associates with CD18 (β2 integrin) to form Mac-1. Mac-1 plays an important role in cell-cell interaction by binding its ligands ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, and fibrinogen. |
