PVALB Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-10575
宿主: Rabbit
反应性: H,M,R
应用: WB,IHC,ELISA
Overview
Synonyms | D22S749,MGC116759,Parvalbumin alpha,PRVA,PVALB,PVALB抗体 |
Swissprot | P20472 |
Source | Rabbit |
Reactivity | Human,Mouse,Rat |
Immunogen | Recombinant protein of human PVALB |
Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213),ELISA |
Recommended dilution | WB 1:200-1:1000, IHC 1:25-1:100 |
Concentration | 0.4 mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Extracellular region or secreted,extracellular exosome,Nucleus,Other locations:cytoplasm,neuronal cell body,protein complex,terminal bouton |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
Background | Parvalbumin is a calcium-binding albumin protein with low molecular weight (typically 9-11 kDa). It has three EF hand motifs and is structurally related to calmodulin and troponin C. Parvalbumin is localised in fast-contracting muscles, where its levels are highest, and in the brain and some endocrine tissues. Parvalbumin is a small, stable protein containing EF-hand type calcium binding sites. It is involved in calcium signaling. Typically, this protein is broken into three domains, domains AB, CD and EF, each individually containing a helix-loop-helix motif. |
Images
Western Blot analysis of Human fetal brain tissue using PVALB Polyclonal Antibody at dilution of 1:400
Immunohistochemistry of paraffin-embedded Human brain using PVALB Polyclonal Antibody at dilution of 1:20
Immunohistochemistry of paraffin-embedded Human breast cancer using PVALB Polyclonal Antibody at dilution of 1:20