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QDPR Polyclonal Antibody

规格: / 20μL / 60μL / 120μL / 200μL
价格: / ¥420 / ¥1010 / ¥1640 / ¥2365

货号:E-AB-52713

宿主: Rabbit

反应性: H,M,R

应用: WB,IHC

  • 详情
  • Overview

    Synonyms 6,7 dihydropteridine reductase,DHPR,DHPR,Dihydropteridine reductase,HDHPR,HPR,PKU2,Qdpr,Quinoid dihydropteridine reductase,SDR33C1,Short chain dehydrogenase/reductase family 33C, member 1,QDPR抗体
    Swissprot P09417
    Source Rabbit
    Reactivity Human,Mouse,Rat
    Immunogen Fusion protein of human QDPR
    Application WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213)
    Recommended dilution WB,,1:500-1:2000;IHC,,1:50-1:200;
    Concentration 1.2mg/mL
    Clonality Polyclonal

    Properties

    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
    Background This gene encodes the enzyme dihydropteridine reductase, which catalyzes the NADH-mediated reduction of quinonoid dihydrobiopterin. This enzyme is an essential component of the pterin-dependent aromatic amino acid hydroxylating systems. Mutations in this gene resulting in QDPR deficiency include aberrant splicing, amino acid substitutions, insertions, or premature terminations. Dihydropteridine reductase deficiency presents as atypical phenylketonuria due to insufficient production of biopterin, a cofactor for phenylalanine hydroxylase.
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