RAMP2 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-15828
宿主: Rabbit
反应性: H
应用: WB
Overview
| Synonyms | Calcitonin receptor like receptor activity modifying protein 2,Calcitonin-receptor-like receptor activity-modifying protein 2,CRLR activity modifying protein 2,CRLR activity-modifying protein 2,OTTMUSP00000002615,OTTMUSP00000037624,RAMP2,RAMP2,Receptor (calcitonin) activity modifying protein 2,Receptor activity modifying protein 2,Receptor activity modifying protein 2 isoform,Receptor activity-modifying protein 2,RP23-281C18.6,RAMP2抗体 |
| Swissprot | O60895 |
| Source | Rabbit |
| Reactivity | Human |
| Immunogen | Synthetic peptide of human RAMP2 |
| Application | WB(Detection kit: E-IR-R304) |
| Recommended dilution | WB,,1:500-1:2000; |
| Concentration | 0.5 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Membrane. |
| Tissue specificity | Strongly expressed in lung, breast, immune system and fetal tissues. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP2) protein, CRLR functions as an adrenomedullin receptor. The RAMP2 protein is involved in core glycosylation and transportation of adrenomedullin receptor to the cell surface. |
