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RBFOX2 Polyclonal Antibody

规格: / 20μL / 60μL / 120μL / 200μL
价格: / ¥420 / ¥1010 / ¥1640 / ¥2365

货号:E-AB-18996

宿主: Rabbit

反应性: H,M,R

应用: IHC

  • 详情
  • Overview

    Synonyms HRNBP2,Fox 1 homologue,Fox-1 homolog B,FOX2,FXH,Hexaribonucleotide-binding protein 2,HNRBP2,RBFOX2,Repressor of tamoxifen transcriptional activity,RFOX2,RNA binding motif protein 9,RNA binding protein 9,RNA binding protein fox-1 homolog 2,RNA-binding motif protein 9,RNA-binding protein 9,RTA,RBFOX2抗体
    Swissprot O43251
    Source Rabbit
    Reactivity Human,Mouse,Rat
    Immunogen Fusion protein of human RBFOX2
    Application IHC(Detection kit: E-IR-R213)
    Recommended dilution IHC,,1:50-1:300
    Concentration 1.44mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Nucleus. Cytoplasm.
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
    Background This gene is one of several human genes similar to the C. elegans gene Fox-1. This gene encodes an RNA binding protein that is thought to be a key regulator of alternative exon splicing in the nervous system and other cell types. The protein binds to a conserved UGCAUG element found downstream of many alternatively spliced exons and promotes inclusion of the alternative exon in mature transcripts. The protein also interacts with the estrogen receptor 1 transcription factor and regulates estrogen receptor 1 transcriptional activity. Multiple transcript variants encoding different isoforms have been found for this gene.
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