RBFOX2 Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-18996
宿主: Rabbit
反应性: H,M,R
应用: IHC
Overview
Synonyms | HRNBP2,Fox 1 homologue,Fox-1 homolog B,FOX2,FXH,Hexaribonucleotide-binding protein 2,HNRBP2,RBFOX2,Repressor of tamoxifen transcriptional activity,RFOX2,RNA binding motif protein 9,RNA binding protein 9,RNA binding protein fox-1 homolog 2,RNA-binding motif protein 9,RNA-binding protein 9,RTA,RBFOX2抗体 |
Swissprot | O43251 |
Source | Rabbit |
Reactivity | Human,Mouse,Rat |
Immunogen | Fusion protein of human RBFOX2 |
Application | IHC(Detection kit: E-IR-R213) |
Recommended dilution | IHC,,1:50-1:300 |
Concentration | 1.44mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Nucleus. Cytoplasm. |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
Background | This gene is one of several human genes similar to the C. elegans gene Fox-1. This gene encodes an RNA binding protein that is thought to be a key regulator of alternative exon splicing in the nervous system and other cell types. The protein binds to a conserved UGCAUG element found downstream of many alternatively spliced exons and promotes inclusion of the alternative exon in mature transcripts. The protein also interacts with the estrogen receptor 1 transcription factor and regulates estrogen receptor 1 transcriptional activity. Multiple transcript variants encoding different isoforms have been found for this gene. |