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RBM19 Polyclonal Antibody

规格: / 20μL / 60μL / 120μL / 200μL
价格: / ¥420 / ¥1010 / ¥1640 / ¥2365

货号:E-AB-18872

宿主: Rabbit

反应性: H,M

应用: IHC

  • 详情
  • Overview

    Synonyms 1200009A02Rik,AV302714,NPO,Probable RNA-binding protein 19,RBM19,RBM19,RNA-binding motif protein 19,RBM19抗体
    Swissprot Q9Y4C8
    Source Rabbit
    Reactivity Human, Mouse
    Immunogen Fusion protein of human RBM19
    Application IHC(Detection kit: E-IR-R213)
    Recommended dilution IHC,,1:40-1:200
    Concentration 0.78mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Nucleus>nucleolus. Nucleus>nucleoplasm. Cytoplasm. Chromosome. In discrete foci distributed throughout the cytoplasm and nucleoplasm during the 4 to 8 cell stages and the morula stage, but not in the periphery of the nucleolar precursor body (NPB). During blastocyst development, becomes increasingly localized to the nucleolus and less to the cytoplasm. At the late blastocyst stage, localized predominantly in the nucleolus. Localized in the nucleolus during interphase and to the perichromosomal sheath during mitosis. Does not colocalize in the cytoplasm with GW182 in P-bodies. May translocate to the nucleolus upon early embryonic development (By similarity). Colocalizes with NPM1 during interphase. By late prophase, metaphase, anaphase and telophase, associates with the chromosome periphery. By telophase localizes to NPB.
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
    Background This gene encodes a nucleolar protein that contains six RNA-binding motifs. The encoded protein may be involved in regulating ribosome biogenesis. Multiple alternatively spliced variants, encoding the same protein, have been identified.
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