RCHY1 Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-52167
宿主: Rabbit
反应性: H,M
应用: WB,IHC
Overview
Synonyms | Androgen receptor N terminal interacting protein,Androgen receptor N-terminal-interacting protein,ARNIP,CH-rich-interacting match with PLAG1,CHIMP,E3 ubiquitin-protein ligase Pirh2,hARNIP,hPirh2,p53 induced protein with a RING H2 domain,p53-induced RING-H2 protein,PIRH2E,PIRH2F,PRO1996,RCHY1,Ring finger and CHY zinc finger domain containing 1 E3 ubiquitin protein ligase,RING finger and CHY zinc finger domain-containing protein 1,RING finger protein 199,RNF199,ZCHY,ZFP 363,zinc finger CHY type,Zinc finger protein 363,ZN363,ZNF363,RCHY1抗体 |
Swissprot | Q96PM5 |
Source | Rabbit |
Reactivity | Human, Mouse |
Immunogen | Fusion protein of human RCHY1 |
Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
Recommended dilution | WB,,1:500-1:2000;IHC,,1:50-1:200; |
Concentration | 0.84mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Nucleus. Nucleus speckle. Cytoplasm. |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
Background | The protein encoded by this gene has ubiquitin ligase activity. It mediates E3-dependent ubiquitination and proteasomal degradation of target proteins, including TP53, HDAC1 and CDKN1B, thus regulating their levels and cell cycle progression. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. |