RDH5 Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-53144
宿主: Rabbit
反应性: H,M
应用: IHC
Overview
Synonyms | 11 cis RDH,11 cis retinol dehydrogenase,9 cis retinol specific dehydrogenase,FLJ39337,FLJ97089,HSD17B9,RDH 5,RDH1,Retinol dehydrogenase 1,Retinol dehydrogenase 5 (11 cis/9 cis),Retinol dehydrogenase 5,SDR9C5,Short chain dehydrogenase/reductase family 9C member 5,RDH5抗体 |
Swissprot | Q92781 |
Source | Rabbit |
Reactivity | Human, Mouse |
Immunogen | Fusion protein of human RDH5 |
Application | IHC(Detection kit: E-IR-R213) |
Recommended dilution | IHC,,1:50-1:100 |
Concentration | 0.84mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Membrane; Peripheral membrane protein |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
Background | This gene encodes an enzyme belonging to the short-chain dehydrogenases/reductases (SDR) family. This retinol dehydrogenase functions to catalyze the final step in the biosynthesis of 11-cis retinaldehyde, which is the universal chromophore of visual pigments. Mutations in this gene cause autosomal recessive fundus albipunctatus, a rare form of night blindness that is characterized by a delay in the regeneration of cone and rod photopigments. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring upstream BLOC1S1 (biogenesis of lysosomal organelles complex-1, subunit 1) gene. |