REST Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-17813
宿主: Rabbit
反应性: H
应用: IHC
Overview
Synonyms | Neural Restrictive Silencer Factor,Neural-restrictive silencer factor,Neuron Restrictive Silencer Factor,NRSF,RE1 silencing transcription factor,RE1-silencing transcription factor,Repressor binding to the X2 box,rest,REST protein,REST,X2 box repressor,XBR,REST抗体 |
Swissprot | Q13127 |
Source | Rabbit |
Reactivity | Human |
Immunogen | Synthetic peptide of human REST |
Application | IHC(Detection kit: E-IR-R213) |
Recommended dilution | IHC,,1:30-1:150 |
Concentration | 1mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Nucleus. |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
Background | This gene encodes a transcriptional repressor that represses neuronal genes in non-neuronal tissues. It is a member of the Kruppel-type zinc finger transcription factor family. It represses transcription by binding a DNA sequence element called the neuron-restrictive silencer element. The protein is also found in undifferentiated neuronal progenitor cells and it is thought that this repressor may act as a master negative regular of neurogenesis. Alternatively spliced transcript variants have been described. |