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REST Polyclonal Antibody

规格: / 20μL / 60μL / 120μL / 200μL
价格: / ¥420 / ¥1010 / ¥1640 / ¥2365

货号:E-AB-17813

宿主: Rabbit

反应性: H

应用: IHC

  • 详情
  • Overview

    Synonyms Neural Restrictive Silencer Factor,Neural-restrictive silencer factor,Neuron Restrictive Silencer Factor,NRSF,RE1 silencing transcription factor,RE1-silencing transcription factor,Repressor binding to the X2 box,rest,REST protein,REST,X2 box repressor,XBR,REST抗体
    Swissprot Q13127
    Source Rabbit
    Reactivity Human
    Immunogen Synthetic peptide of human REST
    Application IHC(Detection kit: E-IR-R213)
    Recommended dilution IHC,,1:30-1:150
    Concentration 1mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Nucleus.
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
    Background This gene encodes a transcriptional repressor that represses neuronal genes in non-neuronal tissues. It is a member of the Kruppel-type zinc finger transcription factor family. It represses transcription by binding a DNA sequence element called the neuron-restrictive silencer element. The protein is also found in undifferentiated neuronal progenitor cells and it is thought that this repressor may act as a master negative regular of neurogenesis. Alternatively spliced transcript variants have been described.
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