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RPS27A Polyclonal Antibody

规格: / 20μL / 60μL / 120μL / 200μL
价格: / ¥420 / ¥1010 / ¥1640 / ¥2365

货号:E-AB-18908

宿主: Rabbit

反应性: H,M,R

应用: IHC

  • 详情
  • Overview

    Synonyms 40S ribosomal protein S27a,CEP 80,CEP80,HUBCEP 80,HUBCEP80,Ribosomal protein S27a,RPS 27A,UBA 80,UBA80,UBCEP 1,UBCEP 80,UBCEP1,UBCEP80,Ubiquitin 40S ribosomal protein S27a,Ubiquitin and ribosomal protein S27a,Ubiquitin carboxyl extension protein 80,Ubiquitin CEP80,RPS27A抗体
    Swissprot P62979
    Source Rabbit
    Reactivity Human,Mouse,Rat
    Immunogen Fusion protein of human RPS27A
    Application IHC(Detection kit: E-IR-R213)
    Recommended dilution IHC,,1:30-1:150
    Concentration 0.72mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Cytosolic small ribosomal subunit,Endoplasmic reticulum,endoplasmic reticulum membrane,endoplasmic reticulum quality control compartment,Endosome membrane,Extracellular region or secreted,extracellular exosome,extracellular space,Mitochondrion,mitochondrial outer membrane,Nucleus,nucleolus,nucleoplasm,nucleus,Plasma Membrane,Other locations:cytoplasm,endocytic vesicle membrane,host cell,membrane,myelin sheath,small ribosomal subunit,vesicle
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
    Background Ubiquitin, a highly conserved protein that has a major role in targeting cellular proteins for degradation by the 26S proteosome, is synthesized as a precursor protein consisting of either polyubiquitin chains or a single ubiquitin fused to an unrelated protein. This gene encodes a fusion protein consisting of ubiquitin at the N terminus and ribosomal protein S27a at the C terminus. When expressed in yeast, the protein is post-translationally processed, generating free ubiquitin monomer and ribosomal protein S27a. Ribosomal protein S27a is a component of the 40S subunit of the ribosome and belongs to the S27AE family of ribosomal proteins. It contains C4-type zinc finger domains and is located in the cytoplasm. Pseudogenes derived from this gene are present in the genome. As with ribosomal protein S27a, ribosomal protein L40 is also synthesized as a fusion protein with ubiquitin; similarly, ribosomal protein S30 is synthesized as a fusion protein with the ubiquitin-like protein fubi. Multiple alternatively spliced transcript variants that encode the same proteins have been identified.
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