RRM1 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-14316
宿主: Rabbit
反应性: H,M
应用: WB
Overview
| Synonyms | R1,Ribonucleoside diphosphate reductase large subunit,Ribonucleoside diphosphate reductase M1 chain,Ribonucleoside diphosphate reductase subunit M1,Ribonucleoside reductase,large subunit,Ribonucleoside-diphosphate reductase large subunit,Ribonucleoside-diphosphate reductase subunit M1,Ribonucleotide reductase large chain,Ribonucleotide reductase large subunit,Ribonucleotide reductase M1,Ribonucleotide reductase M1 polypeptide,Ribonucleotide reductase R1 subunit,Ribonucleotide reductase,M1 subunit,RIR 1,RIR1,RIR1,RR 1,RR1,RRM 1,RRM1,RRM1抗体 |
| Swissprot | P23921 |
| Source | Rabbit |
| Reactivity | Human,Mouse |
| Immunogen | Recombinant protein of human RRM1 |
| Application | WB(Detection kit: E-IR-R304) |
| Recommended dilution | WB,,1:500-1:2000; |
| Concentration | 0.3 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytoplasm. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | This gene encodes one of two non-identical subunits that constitute ribonucleoside-diphosphate reductase, an enzyme essential for the production of deoxyribonucleotides prior to DNA synthesis in S phase of dividing cells. It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region. |
