S100A12 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-40442
宿主: Rabbit
反应性: H
应用: IHC
Overview
| Synonyms | CAAF1, CAGC, Calcitermin, Calcium-binding protein in amniotic fluid 1, Calgranulin C, CGRP, ENRAGE, Extracellular newly identified RAGE-binding protein, migration inhibitory factor-related protein 6, MRP6, Neutrophil S100 protein, p6, Protein S100 A12, S100 calcium binding protein A12, S100A12,S100A12抗体 |
| Swissprot | P80511 |
| Source | Rabbit |
| Reactivity | Human |
| Immunogen | Recombinant Human Protein S100-A12 protein |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:50-1:200 |
| Concentration | 0.5mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cell membrane, Cytoplasm, Cytoskeleton, Membrane, Secreted |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide,1% protective protein and 50% glycerol,pH7.4 |
| Background | The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein is proposed to be involved in specific calcium-dependent signal transduction pathways and its regulatory effect on cytoskeletal components may modulate various neutrophil activities. |
客户发表文献
- 文献: Regulation of S100As Expression by Inflammatory Cytokines in Chronic Lymphocytic Leukemia
样品类型: mononuclear cell (MNCs) - 文献: IL6 inhibition of inflammatory S100A8/9 proteins is NF‐κB mediated in essential thrombocythemia
样品类型: MPN-derived MNC
