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S100A1 Polyclonal Antibody

规格: / 20μL / 60μL / 120μL / 200μL
价格: / ¥420 / ¥1010 / ¥1640 / ¥2365

货号:E-AB-15839

宿主: Rabbit

反应性: H,M,R

应用: IHC

  • 详情
  • Overview

    Synonyms Bpb,NEF,Protein S100-A1,S-100 protein alpha chain,S-100 protein subunit alpha,S100 alpha,S100 beta,S100 calcium binding protein A1,S100 calcium binding protein B,S100 calcium-binding protein A1,S100 protein alpha polypeptide,S100A,s100a1,S100B,S100beta,S10A1,S100A1抗体
    Swissprot P23297
    Source Rabbit
    Reactivity Human,Mouse,Rat
    Immunogen Synthetic peptide of human S100A1
    Application IHC(Detection kit: E-IR-R213)
    Recommended dilution IHC,,1:50-1:200
    Concentration 0.5 mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Cytoplasm.
    Tissue specificity Highly prevalent in heart. Also found in lesser quantities in skeletal muscle and brain.
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
    Background The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-induced Ca2+ release, inhibition of microtubule assembly, and inhibition of protein kinase C-mediated phosphorylation. Reduced expression of this protein has been implicated in cardiomyopathies.
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