S100A1 Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-15839
宿主: Rabbit
反应性: H,M,R
应用: IHC
Overview
Synonyms | Bpb,NEF,Protein S100-A1,S-100 protein alpha chain,S-100 protein subunit alpha,S100 alpha,S100 beta,S100 calcium binding protein A1,S100 calcium binding protein B,S100 calcium-binding protein A1,S100 protein alpha polypeptide,S100A,s100a1,S100B,S100beta,S10A1,S100A1抗体 |
Swissprot | P23297 |
Source | Rabbit |
Reactivity | Human,Mouse,Rat |
Immunogen | Synthetic peptide of human S100A1 |
Application | IHC(Detection kit: E-IR-R213) |
Recommended dilution | IHC,,1:50-1:200 |
Concentration | 0.5 mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Cytoplasm. |
Tissue specificity | Highly prevalent in heart. Also found in lesser quantities in skeletal muscle and brain. |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
Background | The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-induced Ca2+ release, inhibition of microtubule assembly, and inhibition of protein kinase C-mediated phosphorylation. Reduced expression of this protein has been implicated in cardiomyopathies. |