S100A4 Monoclonal Antibody
| 规格： | / 60μL / 120μL |
| 价格： | / ￥1420 / ￥2310 |
货号：E-AB-70355
宿主: Mouse
反应性: H,M,R
应用: IHC
Overview
| Synonyms | 18A2,42A,calcium Placental protein,Calvasculin,CAPL,Fibroblast specific protein 1 (FSP1),Fibroblast specific protein 1,Fibroblast specific protein,FSP1,Leukemia multidrug resistance associated protein,Malignant transformation suppression 1 (MTS1),Malignant transformation suppression 1,Metastasin,MTS1,OTTHUMP00000015467,OTTHUMP00000015468,P9KA,PEL98,Placental calcium-binding protein,Protein Mts1,Protein S100 A4,Protein S100-A4,S100 calcium binding protein A4 (calcium protein,calvasculin,metastasin,murine placental homolog),S100 calcium binding protein A4,S100 calcium-binding protein A4,S100a4,S10A4,S100A4抗体 |
| Swissprot | P26447,P07091,P05942 |
| Source | Mouse |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Recombinant protein corresponding to Mouse S100A4 |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:200-1:800 |
| Concentration | 1 mg/mL |
| Clonality | Monoclonal |
Properties
| Clone No | 3A6H9 |
|---|---|
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol. |
| Background | S100A4 is a member of the S100 family of calcium-binding proteins. The S100 family members have been involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100A4 is known to localize to and function in the nucleus, cytoplasm of cells and the extracellular space. S100A4 has also been shown to be associated with tumor growth, motility, invasion, metastasis, angiogenesis, apoptosis and chemoresistance. It is a fibroblast-specific protein associated with mesenchymal cell morphology and motility, is expressed during epithelial-mesenchymal transformations (EMT) in vivo. It is an improved marker for lung fibroblasts that could be useful for investigating the pathogenesis of pulmonary fibrosis. Overexpression of S100A4 is correlated with a worse prognosis inpatients with various types of cancer. |
Images
Immunohistochemistry analysis of paraffin-embedded human lymphoma using S100A4 Monoclonal Antibody at dilution of 1:300.
Immunohistochemistry analysis of paraffin-embedded mouse colon using S100A4 Monoclonal Antibody at dilution of 1:300.
Immunohistochemistry analysis of paraffin-embedded Rat brain using S100A4 Monoclonal Antibody at dilution of 1:300.
