SARS-CoV-2 E Protein Polyclonal Antibody(2019-nCoV)
规格: | / 50μL / 100μL |
价格: | / ¥2000 / ¥3320 |
货号:E-AB-V1033
宿主: Rabbit
应用: ELISA
Overview
Synonyms | 2019-nCoV E protein,2019-nCoV sM protein,Envelope small membrane protein,SARS-CoV-2 E Protein抗体 |
Source | Rabbit |
Reactivity | SARS-COV2 |
Immunogen | Recombinant SARS-CoV-2 E protein |
Application | ELISA |
Recommended dilution | ELISA,,1:4000~1:8000; |
Concentration | 0.30mg/ml |
Properties
Isotype | IgG |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS, pH7.4, containing 0.05% proclin300, 50% glycerol. |
Background | Coronavirus envelope (E) proteins are short (100 residues) polypeptides that contain at least one transmembrane (TM) domain and a cluster of 2-3 juxtamembrane cysteines. These proteins are involved in viral morphogenesis and tropism, and their absence leads in some cases to aberrant virions, or to viral attenuation. In common to other viroporins, coronavirus envelope proteins increase membrane permeability to ions, plays a central role in virus morphogenesis and assembly. Acts as a viroporin and self-assembles in host membranes forming pentameric protein-lipid pores that allow ion transport. Also plays a role in the induction of apoptosis. Activates the host NLRP3 inflammasome, leading to IL-1beta overproduction. |