SARS-CoV-2 NSP3 Polyclonal Antibody(2019-nCoV)
| 规格： | / 50μL / 100μL |
| 价格： | / ￥2000 / ￥3320 |
货号：E-AB-V1039
宿主: Rabbit
应用: ELISA
Overview
| Synonyms | Non-structural protein 3,PL2-PRO,Papain-like proteinase,PL-PRO,Replicase polyprotein 1a,SARS-CoV-2 NSP3抗体 |
| Source | Rabbit |
| Reactivity | SARS-COV2 |
| Immunogen | Recombinant SARS-CoV-2 NSP3 |
| Application | ELISA |
| Recommended dilution | ELISA,,1:4000~1:8000; |
| Concentration | 0.33mg/ml |
Properties
| Isotype | IgG |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS, pH7.4, containing 0.05% proclin300, 50% glycerol. |
| Background | Responsible for the cleavages located at the N-terminus of the replicase polyprotein. In addition, PL-PRO possesses a deubiquitinating/deISGylating activity and processes both 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains from cellular substrates. Participates together with nsp4 in the assembly of virally-induced cytoplasmic double-membrane vesicles necessary for viral replication. Antagonizes innate immune induction of type I interferon by blocking the phosphorylation, dimerization and subsequent nuclear translocation of host IRF3. Prevents also host NF-kappa-B signaling. |
