SCCPDH Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-19034
宿主: Rabbit
反应性: H,M,R
应用: WB,IHC
Overview
| Synonyms | CGI 49,CGI49,FLJ43187,Probable saccharopine dehydrogenase,Saccharopine dehydrogenase,SCCPDH,SCPDH,SCCPDH抗体 |
| Swissprot | Q8NBX0 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Fusion protein of human SCCPDH |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:1000-1:5000;IHC,,1:50-1:300; |
| Concentration | 1.5mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Extracellular region or secreted,extracellular region,Mitochondrion,Nucleus,Other locations:lipid droplet,membrane,midbody,platelet alpha granule lumen |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | SCCPDH (Probable saccharopine dehydrogenase) is a 429 amino acid protein that belongs to the saccharopine dehydrogenase family. The SCCPDH gene is conserved in chimpanzee, dog, cow, mouse, rat, chicken, fruit fly, mosquito and C.elegans, and maps to human chromosome 1q44. Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma. |
Images
Western blot analysis of Human fetal liver tissue PC-3 and A172 cell lysates using SCCPDH Polyclonal Antibody at dilution of 1:1000
Immunohistochemistry of paraffin-embedded Human tonsil tissue using SCCPDH Polyclonal Antibody at dilution of 1:85(×200)
Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using SCCPDH Polyclonal Antibody at dilution of 1:85(×200)
